| The Do Something Award | Athlete | City |
| Comedian | Couple | Film |
| Movie Star: Female | Movie Star: Male | |
| Music Artist | Reality TV Show | Style |
| TV Show | TV Star: Female | TV Star: Male |
DO SOMETHING Style
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Giuliana Rancic
After being diagnosed with cancer, Giuliana vowed to fight against the disease and started Bright Pink (a cancer awareness charity). She is also an advocate for Operation Smile.
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Nicki Minaj & Ricky Martin
The singers teamed up to be the faces of the MAC Viva Glam line and a new campaign to bring HIV/AIDS awareness to Latin America with proceeds going directly to support activities raising awareness of HIV/AIDS in Latin America.
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Heidi Klum
Heidi Klum lit the Empire State Building Red and white to raise awareness for DKMS in the fight against blood cancer. She is also a dedicated supporter of children's health and welfare through her work with UNICEF and the Children's Hospital.
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Nicole Richie
Nicole founded the Richie Madden Foundation with husband Joel Madden, working in association with the Los Angeles Free Clinic to help disadvantaged families.
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Cindy Crawford
Crawford has been a long-time supporter of the pediatric oncology program at the University of Wisconsin-Madison, she is also an honorary board member of the Multiple Myeloma Research Foundation and an official supporter of the Ronald McDonald House Charities.
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